Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complexity of VEGF responses in skin carcinogenesis revealed through ex vivo assays based on a VEGF-A null mouse keratinocyte cell line.

The Journal of investigative dermatology - 1 Mar 2009

Mirones Isabel, Conti Claudio J, Martínez Jesús, Garcia Marta, Larcher Fernando

Abstract excerpt

Vascular endothelial growth factor (VEGF-A) is a critical player in cutaneous angiogenesis. However, the relative contribution of VEGF-A from different sources including epithelial and mesenchymal cells has not been fully characterized during skin repair and tumorigenesis. Moreover, the actual involvement of other vascular-specific acting molecules has remained elusive in part due to the masking and/or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoviridae
Share to Gene Transfer Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Keratinocytes

Share to Neoplasm Metastasis

Share to Neovascularization, Pathologic

Share to ras Proteins

Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 18818673
DOI: 10.1038/jid.2008.292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complexity of VEGF responses in skin carcinogenesis revealed through ex vivo assays based on a VEGF-A null mouse keratinocyte cell line.PMID 18818673Read ↗

Multiple Roles for VEGF in Non-Melanoma Skin Cancer: Angiogenesis and BeyondSemantic proximity Read ↗

Modulation of the angiogenesis response through Ha-ras control, placenta growth factor, and angiopoietin expression in mouse skin carcinogenesis.Semantic proximity Read ↗

Unexpected autocrine role of vascular endothelial growth factor in squamous cell carcinoma.Semantic proximity Read ↗

VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sproutingSemantic proximity Read ↗

Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasisSemantic proximity Read ↗

Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions.Semantic proximity Read ↗

Halting angiogenesis by non-viral somatic gene therapy alleviates psoriasis and murine psoriasiform skin lesionsSemantic proximity Read ↗

Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.Semantic proximity Read ↗

FOXO1 regulates VEGFA expression and promotes angiogenesis in healing woundsSemantic proximity Read ↗

The Human Herpes Virus 8-Encoded Chemokine Receptor Is Required for Angioproliferation in a Murine Model of Kaposi’s SarcomaSemantic proximity Read ↗

Genetically Modified Human Epidermis Overexpressing PDGF-A Directs the Development of a Cellular and Vascular Connective Tissue Stroma When Transplanted to Athymic Mice–Implications for the Use of Genetically Modified Keratinocytes to Modulate Dermal RegenerationSemantic proximity Read ↗

The up-regulation of vascular endothelial growth factor in mutated Ha-ras HaCaT cell lines is reduced by a farnesyl transferase inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.