Article
[Cell phenotype determines PAI-1 antiproliferative effect - suppressed proliferation of the lung cancer but not prostate cancer cells].
Pneumonologia i alergologia polska - 1 Jan 2010
Chorostowska-Wynimko Joanna, Kedzior Marta, Struniawski Radosław, Jaguś Paulina, Skrzypczak-Jankun Ewa, Jankun Jerzy
Abstract excerpt
INTRODUCTION: Plasminogen inhibitor activator type 1 (PAI-1) is an important regulator of tumor growth and metastasis formation acting directly via specific urokinase complexing or indirectly due to its affinity to vitronectin. We have shown previously that PAI-1 modifies angiogenic activity of e...
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