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Article

<i>Nmyc</i>plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

17 Feb 2005

Abstract excerpt

Understanding how lung progenitor cells balance proliferation against differentiation is relevant to clinical disorders such as bronchopulmonary dysplasia of premature babies and lung cancer. Previous studies have established that lung development is severely disrupted in mouse mutants with reduced levels of the proto-oncogene Nmyc, but the precise mechanisms involved have not been explored. We show here that...

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PMID: 15716345
DOI: 10.1242/dev.01678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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