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Article

Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia

22 Oct 2016

Abstract excerpt

Abstract Inflammation‐induced FGF10 protein deficiency is associated with bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely born infants characterized by arrested alveolar development. So far, experimental evidence for a direct role of FGF10 in lung disease is lacking. Using the hyperoxia‐induced neonatal lung injury as a mouse model of BPD, the impact of Fgf10 deficiency in Fgf10+/− versus...

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PMID: 27770432
DOI: 10.1002/path.4834

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