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Article

SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling

19 Sept 2022

Abstract excerpt

The balance between self-renewal and differentiation in human foetal lung epithelial progenitors controls the size and function of the adult organ. Moreover, progenitor cell gene regulation networks are employed by both regenerating and malignant lung cells, where modulators of their effects could potentially be of therapeutic value. Details of the molecular networks controlling human lung progenitor self-renewal...

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PMID: 36121125
DOI: 10.15252/embj.2022111338

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