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Article

CD40 signaling induces reciprocal outcomes in Leishmania-infected macrophages; roles of host genotype and cytokine milieu.

Microbes and infection - 1 Jan 2005

Nunes Marise P, Cysne-Finkelstein Lea, Monteiro Bruna C, de Souza Daniel M, Gomes Nitza A, DosReis George A

Abstract excerpt

We investigated the influence of CD40-CD40 ligand-mediated signaling on induction of microbicidal activity against Leishmania major in macrophages from resistant (B6) and susceptible (BALB) mouse strains. CD40 engagement induced leishmanicidal activity in resistant macrophages, but increased para...

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Source

Identifiers

PMID: 15716074
DOI: 10.1016/j.micinf.2004.08.022

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15716074-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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