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Article

Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB/c mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2007

Nigg Axel P, Zahn Sabine, Rückerl Dominik, Hölscher Christoph, Yoshimoto Takayuki, Ehrchen Jan M, Wölbing Florian, Udey Mark C, von Stebut Esther

Abstract excerpt

Protection against Leishmania major in resistant C57BL/6 mice is mediated by Th1 cells, whereas susceptibility in BALB/c mice is the result of Th2 development. IL-12 release by L. major-infected dendritic cells (DC) is critically involved in differentiation of Th1 cells. Previously, we reported t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17513774
DOI: 10.4049/jimmunol.178.11.7251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17513774-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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