The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major.

doi:10.4049/jimmunol.170.10.5152

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The relative contribution of IL-4 receptor signaling and IL-10 to susceptibility to Leishmania major.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2003

Noben-Trauth Nancy, Lira Rosalia, Nagase Hisashi, Paul William E, Sacks David L

Abstract excerpt

The roles of IL-10 and IL-4 receptor signaling were evaluated in a murine model of Leishmania major infection. In previous studies the L. major substrain LV39 caused progressive, nonhealing lesions in BALB/c mice deficient for IL-4R alpha-chain (IL-4R alpha), while substrain IR173 was highly controlled. To explore whether IL-10 is responsible for inducing susceptibility to LV39, wild-type and IL-4R alpha(-/-)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Antigens
Share to Injections, Intraperitoneal
Share to Leishmania major
Share to Leishmaniasis, Cutaneous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophage Activation

Share to Macrophages, Peritoneal

Share to Receptors, Interleukin

Share to Receptors, Interleukin-4

Source

Open in PubMed

Identifiers

PMID: 12734362
DOI: 10.4049/jimmunol.170.10.5152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.