Article
The nuclear exosome contributes to autogenous control of NAB2 mRNA levels.
Molecular and cellular biology - 1 Mar 2005
Roth Kelly M, Wolf Maria K, Rossi Marie, Butler J Scott
Abstract excerpt
The RNA-processing exosome is a complex of riboexonucleases required for 3'-end formation of some noncoding RNAs and for the degradation of mRNAs in eukaryotes. The nuclear form of the exosome functions in an mRNA surveillance pathway that retains and degrades improperly processed precursor mRNAs within the nucleus. We report here that the nuclear exosome controls the level of NAB2 mRNA, encoding the nuclear...
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