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Article

Nuclear mRNA Surveillance Mechanisms: Function and Links to Human Disease.

Journal of molecular biology - 6 Jul 2018

Singh Pragyan, Saha Upasana, Paira Sunirmal, Das Biswadip

Abstract excerpt

Production of export-competent mRNAs involves transcription and a series of dynamic processing and modification events of pre-messenger RNAs in the nucleus. Mutations in the genes encoding the transcription and mRNP processing machinery and the complexities involved in the biogenesis events lead to the formation of aberrant messages. These faulty transcripts are promptly eliminated by the nuclear RNA exosome and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29758258
DOI: 10.1016/j.jmb.2018.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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