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Article

Temporal regulation of adenovirus major late alternative RNA splicing

1 Jan 2008

Abstract excerpt

Adenovirus makes extensive use of alternative RNA splicing to produce a complex set of spliced mRNAs during replication. The accumulation of viral mRNAs is subjected to a temporal regulation, a mechanism that ensures that proteins that are needed at certain stages of the virus life cycle are produced in a timely fashion. The complex interactions between the virus and the host cell RNA splicing machinery has been...

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PMID: 18508565
DOI: 10.2741/3059

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