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Article

Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer.

Cancer research - 1 Feb 2005

Zhang Xuemei, Miao Xiaoping, Liang Gang, Hao Bingtao, Wang Yonggang, Tan Wen, Li Yi, Guo Yongli, He Fuchu, Wei Qingyi, Lin Dongxin

Abstract excerpt

Adenosine diphosphate ribosyl transferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are two major DNA base excision repair (BER) proteins and act interactively in stimulating and executing BER processes. Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Gln have been associated with altered protein function and BER activity. This case-control study examined the contribution of these two polymorphisms,...

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Source

Identifiers

PMID: 15705867

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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