Article
Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer.
Cancer research - 1 Mar 2002
Zhou Wei, Liu Geoffrey, Miller David P, Thurston Sally W, Xu Li Lian, Wain John C, Lynch Thomas J, Su Li, Christiani David C
Abstract excerpt
Excision repair cross-complementing group 2 (ERCC2), a major DNA repair protein, is involved in nucleotide excision repair and basal transcription. The ERCC2 polymorphisms have been associated with altered DNA repair capacity. We investigated two ERCC2 polymorphisms, Asp312Asn and Lys751Gln, in 1...
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