Article
[Study of relationship between ApoE epsilon4 allele and hippocampal atrophy in Alzheimer disease].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Jan 2005
Li Jin, Kuang Wei-hong, Li Jing, Wang Xue, Huang Ming-sheng, Wu Ding-ping
Abstract excerpt
OBJECTIVE: To investigate the relationship between ApoE epsilon4 allele and hippocampal atrophy in patients with AD. METHODS: Using MRI-based volumetry technique and PCR-FRLP, the hippocampal volume and ApoE genotype of 34 AD patients were examined, and the difference in hippocampal volume between the ApoE epsilon4 positive AD group (n=17) and the ApoE epsilon4 negative AD group (n=17) was analyzed. The...
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