Article
Location of cis-acting signals important for RNA encapsidation in the leader sequence of human immunodeficiency virus type 2.
Journal of virology - 1 May 1997
McCann E M, Lever A M
Abstract excerpt
We used a series of deletion mutations in the untranslated leader region of human immunodeficiency virus type 2 (HIV-2) to seek cis-acting packaging signals. Sequences between the 5' major splice donor and the gag initiation codon, where such signals have been identified in HIV-1, appear to make a measurable but very minor contribution to genomic RNA packaging, and deletions here had little effect on viral...
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