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Article

A conditional-lethal vaccinia virus mutant demonstrates that the I7L gene product is required for virion morphogenesis.

Virology journal - 8 Feb 2005

Byrd Chelsea M, Hruby Dennis E

Abstract excerpt

A conditional-lethal recombinant virus was constructed in which the expression of the vaccinia virus I7L gene is under the control of the tetracycline operator/repressor system. In the absence of I7L expression, processing of the major VV core proteins is inhibited and electron microscopy reveals defects in virion morphogenesis subsequent to the formation of immature virion particles but prior to core...

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Identifiers

PMID: 15701171
DOI: 10.1186/1743-422X-2-4
PMCID: PMC548685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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