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Article

IPTG-dependent vaccinia virus: identification of a virus protein enabling virion envelopment by Golgi membrane and egress.

Nucleic acids research - 25 Sept 1990

Rodriguez J F, Smith G L

Abstract excerpt

A novel method has been developed to study the functional roles of individual vaccinia virus gene products that is neither limited by the possible essentiality of the target gene nor by the availability of conditional lethal mutants. The system utilises the E. coli lac repressor protein, the operator sequence to which it binds and the specific inducer IPTG. It allows the generation of recombinant viruses in which...

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Identifiers

PMID: 2216706
DOI: 10.1093/nar/18.18.5347
PMCID: PMC332208

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