Article
Vaccinia virus morphogenesis: a13 phosphoprotein is required for assembly of mature virions.
Journal of virology - 1 Aug 2004
Unger Bethany, Traktman Paula
Abstract excerpt
The 70-amino-acid A13L protein is a component of the vaccinia virus membrane. We demonstrate here that the protein is expressed at late times of infection, undergoes phosphorylation at a serine residue(s), and becomes encapsidated in a monomeric form. Phosphorylation is dependent on Ser40, which lies within the proline-rich motif SPPP. Because phosphorylation of the A13 protein is only minimally affected by...
Topics
- Amino Acid Sequence
- Cell Line
- Gene Expression Regulation, Viral
- Genes, Essential
- Microscopy, Electron
- Molecular Sequence Data
- Morphogenesis
- Mutation
- Phosphoproteins
- Phosphorylation
- Structure-Activity Relationship
- Temperature
- Vaccinia virus
- Viral Envelope Proteins
- Virion
- Virus Assembly
