Article
Involvement of spicules in the formation of vaccinia virus envelopes elucidated by a conditional lethal mutant.
Virology - 20 Dec 1995
Mohandas A R, Dales S
Abstract excerpt
The envelope of immature vaccinia virions consists of a lipoprotein bilayer upon which a precise curvature is imposed by acquisition of an external scaffold of spicules. Self-assembly of this tegument was examined employing our ts 6757 mutant, which induces accumulation of immature envelopes at the restrictive temperature. With ts 6757 the envelope bilayers were also assembled into an alternative membrane...
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