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Toll-like receptor 2 and type 2 diabetes

28 Jul 2016

Abstract excerpt

Innate immunity plays a crucial role in the pathogenesis of type 2 diabetes and related complications. Since the toll-like receptors (TLRs) are central to innate immunity, it appears that they are important participants in the development and pathogenesis of the disease. Previous investigations demonstrated that TLR2 homodimers and TLR2 heterodimers with TLR1 or TLR6 activate innate immunity upon recognition of...

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PMID: 28536605
DOI: 10.1186/s11658-016-0002-4

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