Article
Solution structure of the Tctex1 dimer reveals a mechanism for dynein-cargo interactions.
Structure (London, England : 1993) - 1 Feb 2005
Wu Hongwei, Maciejewski Mark W, Takebe Sachiko, King Stephen M
Abstract excerpt
Tctex1 is a light chain found in both cytoplasmic and flagellar dyneins and is involved in many fundamental cellular activities, including rhodopsin transport within photoreceptors, and may function in the non-Mendelian transmission of t haplotypes in mice. Here, we present the NMR solution structure for the Tctex1 dimer from Chlamydomonas axonemal inner dynein arm I1. Structural comparisons reveal a strong...
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