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Article

Novel LC8 mutations have disparate effects on the assembly and stability of flagellar complexes.

The Journal of biological chemistry - 6 Nov 2009

Yang Pinfen, Yang Chun, Wirschell Maureen, Davis Stephanie

Abstract excerpt

LC8 functions as a dimer crucial for a variety of molecular motors and non-motor complexes. Emerging models, founded on structural studies, suggest that the LC8 dimer promotes the stability and refolding of dimeric target proteins in molecular complexes, and its interactions with selective target proteins, including dynein subunits, is regulated by LC8 phosphorylation, which is proposed to prevent LC8...

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Identifiers

PMID: 19696030
DOI: 10.1074/jbc.M109.050666
PMCID: PMC2781537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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