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A doublecortin-domain protein of <i>Toxoplasma</i> and its orthologues bind to and modify the structure and organization of tubulin polymers

2019-04-30

Abstract excerpt

<h4>ABSTRACT</h4> TgDCX is a doublecortin-domain protein associated with the conoid fibers, a set of strongly curved non-tubular tubulin-polymers in Toxoplasma . TgDCX deletion impairs conoid structure and parasite invasion. TgDCX contains two tubulin-binding domains: a partial P25-alpha and the DCX/doublecortin domain. Orthologues are found in apicomplexans and their free-living relatives Chromera and Vitrell...

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Literature Corpus work
99c1e869-80de-5315-a8b9-b7073ee8e056
DOI
10.1101/623140
Open publication

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