Article
Structure of Tctex-1 and its interaction with cytoplasmic dynein intermediate chain.
The Journal of biological chemistry - 27 Apr 2001
Mok Y K, Lo K W, Zhang M
Abstract excerpt
The minus-ended microtubule motor cytoplasmic dynein contains a number of low molecular weight light chains including the 14-kDa Tctex-1. The assembly of Tctex-1 in the dynein complex and its function are largely unknown. Using partially deuterated, (15)N,(13)C-labeled protein samples and transverse relaxation-optimized NMR spectroscopic techniques, the secondary structure and overall topology of Tctex-1 were...
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