Article
Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms.
PLoS genetics - 1 Sept 2017
Yamamoto Ryosuke, Obbineni Jagan M, Alford Lea M, Ide Takahiro, Owa Mikito, Hwang Juyeon, Kon Takahide, Inaba Kazuo, James Noliyanda, King Stephen M, Ishikawa Takashi, Sale Winfield S, Dutcher Susan K
Abstract excerpt
Cytoplasmic assembly of ciliary dyneins, a process known as preassembly, requires numerous non-dynein proteins, but the identities and functions of these proteins are not fully elucidated. Here, we show that the classical Chlamydomonas motility mutant pf23 is defective in the Chlamydomonas homolog of DYX1C1. The pf23 mutant has a 494 bp deletion in the DYX1C1 gene and expresses a shorter DYX1C1 protein in the...
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