Article
Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis.
The Journal of allergy and clinical immunology - 1 Feb 2005
Corrigan Chris, Mallett Kirsty, Ying Sun, Roberts David, Parikh Abhi, Scadding Glenis, Lee Tak
Abstract excerpt
BACKGROUND: Cysteinyl leukotrienes play a disease-regulating role in rhinosinusitis and asthma, particularly aspirin-sensitive disease. They act through 2 G-protein coupled receptors termed cysteinyl leukotriene type 1 receptor (cysLT 1 ) and cysteinyl leukotriene type 2 receptor (cysLT 2 ). We previously compared expression of cysLT 1 on mucosal leukocytes in patients with aspirin-sensitive and aspirin-tolerant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.