Article
Pathogenesis of Aspirin-Induced Reactions in Aspirin-Exacerbated Respiratory Disease.
Immunology and allergy clinics of North America - 1 Nov 2016
Cahill Katherine N, Laidlaw Tanya M
Abstract excerpt
The acute clinical symptoms that develop following the oral ingestion of aspirin, or any other inhibitor of cyclooxygenase-1, are well established in aspirin-exacerbated respiratory disease: nasal congestion, rhinorrhea, and bronchospasm. Less commonly, gastrointestinal distress, rash, angioedema, or urticaria also develops. However, the pathobiology that drives these clinical reactions is poorly understood. Use...
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