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Article

Epithelial folliculin enhances airway inflammation in aspirin-exacerbated respiratory disease.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2018

Trinh Hoang Kim Tu, Pham Duy Le, Choi Youngwoo, Kim Hyun-Mi, Kim Seung-Hyun, Park Hae-Sim

Abstract excerpt

BACKGROUND: Clinical features of aspirin-exacerbated respiratory disease (AERD) are characterized by overproduction of cysteinyl leukotrienes (LT) and eosinophil activation, in which epithelial cells contribute to eosinophilic airway inflammation. Folliculin (FLCN) helps maintain the integrity of epithelial barrier, but little is known about FLCN in AERD. OBJECTIVE: We investigated the role of FLCN in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30126026
DOI: 10.1111/cea.13253

Genes

FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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