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Article

Pathophysiologic consequences following inhibition of a CFTR-dependent developmental cascade in the lung.

BMC developmental biology - 4 Feb 2005

Cohen J Craig, Larson Janet E

Abstract excerpt

BACKGROUND: Examination of late gestation developmental genes in vivo may be limited by early embryonic lethality and compensatory mechanisms. This problem is particularly apparent in evaluating the developmental role of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in the cystic fibrosis (CF) phenotype. A previously described transient in utero knockout (TIUKO) technology was used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

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Share to Rats, Sprague-Dawley

Source

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Identifiers

PMID: 15694001
DOI: 10.1186/1471-213X-5-2
PMCID: PMC549215

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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