Article
Evolutionary analysis of hepatitis C virus gene sequences from 1953.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Sept 2013
Gray Rebecca R, Tanaka Yasuhito, Takebe Yutaka, Magiorkinis Gkikas, Buskell Zelma, Seeff Leonard, Alter Harvey J, Pybus Oliver G
Abstract excerpt
Reconstructing the transmission history of infectious diseases in the absence of medical or epidemiological records often relies on the evolutionary analysis of pathogen genetic sequences. The precision of evolutionary estimates of epidemic history can be increased by the inclusion of sequences derived from 'archived' samples that are genetically distinct from contemporary strains. Historical sequences are...
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