Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in <i>Escherichia</i> coli

1 Jan 1992

Abstract excerpt

A cDNA encoding the complete normal human p53 protein was expressed in Escherichia coli using an expression system based on the bacteriophage T7 promoter. The cDNA was adapted so that the full-length protein was produced without fusion to any other sequence. Large amounts of the protein were isolated and the purified protein used to produce very high titre polyclonal antibodies to p53. These new antibodies permit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cancer-related Molecular Pathways
Share to Cancer Research and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1569122
DOI: 10.1242/jcs.101.1.183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in <i>Escherichia</i> coliPMID 1569122Read ↗

p53 expression in human breast cancer.Semantic proximity Read ↗

Use of specific ELISA for the detection of antibodies directed against p53 protein in patients with hepatocellular carcinoma.Semantic proximity Read ↗

Genetic basis for p53 overexpression in human breast cancer.Semantic proximity Read ↗

Regulation of p53 protein expression in human breast cancer cell lines.Semantic proximity Read ↗

The humoral immune response to p53 in patients with hepatocellular carcinoma is specific for malignancy and independent of the alpha-fetoprotein status.Semantic proximity Read ↗

Mutant p53, EGF receptor and c-erbB-2 expression in human breast cancer.Semantic proximity Read ↗

Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.Semantic proximity Read ↗

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.Semantic proximity Read ↗

Prognostic significance of p53 overexpression in primary breast cancer; a novel luminometric immunoassay applicable on steroid receptor cytosols.Semantic proximity Read ↗

The p53 tumor suppressor gene. A preliminary clinical study in breast cancer patients.Semantic proximity Read ↗

Enzyme-linked immunosorbent assay for p53 in gastrointestinal malignancy: comparison with immunohistochemistry.Semantic proximity Read ↗

The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.