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Article

Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Feb 2005

Lee Hyosang, Iida Tohko, Mizuno Atsuko, Suzuki Makoto, Caterina Michael J

Abstract excerpt

Transient receptor potential vanilloid 4 (TRPV4), a cation channel responsive to hypotonicity, can also be activated by warm temperatures. Moreover, TRPV4-/- mice reportedly exhibit deficits in inflammation-induced thermal hyperalgesia. However, it is unknown whether TRPV4 or related transient receptor potential channels account for warmth perception under injury-free conditions. We therefore investigated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15689568
DOI: 10.1523/JNEUROSCI.4745.04.2005
PMCID: PMC6725965

Genes

TRPV4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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