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Article

Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Feb 2011

Garami Andras, Pakai Eszter, Oliveira Daniela L, Steiner Alexandre A, Wanner Samuel P, Almeida M Camila, Lesnikov Vladimir A, Gavva Narender R, Romanovsky Andrej A

Abstract excerpt

This study aimed at determining the thermoregulatory phenotype of mice lacking transient receptor potential vanilloid-1 (TRPV1) channels. We used Trpv1 knockout (KO) mice and their genetically unaltered littermates to study diurnal variations in deep body temperature (T(b)) and thermoeffector activities under basal conditions, as well as thermoregulatory responses to severe heat and cold. Only subtle alterations...

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Identifiers

PMID: 21289181
DOI: 10.1523/JNEUROSCI.4671-10.2011
PMCID: PMC3430466

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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