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Article

Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays.

Genetics - 1 Jan 2003

Winzeler Elizabeth A, Castillo-Davis Cristian I, Oshiro Guy, Liang David, Richards Daniel R, Zhou Yingyao, Hartl Daniel L

Abstract excerpt

The availability of a complete genome sequence allows the detailed study of intraspecies variability. Here we use high-density oligonucleotide arrays to discover 11,115 single-feature polymorphisms (SFPs) existing in one or more of 14 different yeast strains. We use these SFPs to define regions of genetic identity between common laboratory strains of yeast. We assess the genome-wide distribution of genetic...

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Identifiers

PMID: 12586698
DOI: 10.1093/genetics/163.1.79
PMCID: PMC1462430

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