Article
Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains.
PloS one - 28 Mar 2007
Schacherer Joseph, Ruderfer Douglas M, Gresham David, Dolinski Kara, Botstein David, Kruglyak Leonid
Abstract excerpt
Ten years have passed since the genome of Saccharomyces cerevisiae-more precisely, the S288c strain-was completely sequenced. However, experimental work in yeast is commonly performed using strains that are of unknown genetic relationship to S288c. Here, we characterized the nucleotide-level similarity between S288c and seven commonly used lab strains (A364A, W303, FL100, CEN.PK, summation 1278b, SK1 and BY4716)...
Topics
- Chromosomes, Fungal
- Genetic Variation
- Genome, Fungal
- Genome-Wide Association Study
- Nucleic Acid Hybridization
- Nucleotides
- Oligonucleotide Array Sequence Analysis
- Polymorphism, Single Nucleotide
- Saccharomyces cerevisiae
- Sequence Deletion