Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amino-terminal protein fusions to the TraR quorum-sensing transcription factor enhance protein stability and autoinducer-independent activity.

Journal of bacteriology - 1 Feb 2005

Chai Yunrong, Winans Stephen C

Abstract excerpt

TraR of Agrobacterium tumefaciens is a member of the LuxR family of quorum-sensing transcription factors and regulates genes required for conjugation and vegetative replication of the tumor-inducing (Ti) plasmid in the presence of the autoinducer 3-oxooctanoyl-homoserine lactone (OOHL). In the absence of OOHL, TraR is rapidly destroyed by proteolysis, suggesting that this ligand is required for TraR folding. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to DNA Mutational Analysis

Share to Gene Expression Regulation, Bacterial

Share to Homoserine

Share to Plasmids

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15687185
DOI: 10.1128/JB.187.4.1219-1226.2005
PMCID: PMC545634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amino-terminal protein fusions to the TraR quorum-sensing transcription factor enhance protein stability and autoinducer-independent activity.PMID 15687185Read ↗

Identification of amino acid residues of the Agrobacterium tumefaciens quorum-sensing regulator TraR that are critical for positive control of transcription.Semantic proximity Read ↗

The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.Semantic proximity Read ↗

Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR.Semantic proximity Read ↗

Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR.Semantic proximity Read ↗

Identification of amino acid residues of the pheromone-binding domain of the transcription factor TraR that are required for positive control.Semantic proximity Read ↗

Domains formed within the N-terminal region of the quorum-sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from agrobacterium.Semantic proximity Read ↗

Error-prone PCR mutagenesis reveals functional domains of a bacterial transcriptional activator, TraJ.Semantic proximity Read ↗

N- and C-terminal regions of the quorum-sensing activator TraR cooperate in interactions with the alpha and sigma-70 components of RNA polymerase.Semantic proximity Read ↗

The quorum sensing transcriptional regulator TraR has separate binding sites for DNA and the anti-activator.Semantic proximity Read ↗

A new regulatory element modulates homoserine lactone-mediated autoinduction of Ti plasmid conjugal transfer.Semantic proximity Read ↗

The Agrobacterium tumefaciens rnd homolog is required for TraR-mediated quorum-dependent activation of Ti plasmid tra gene expression.Semantic proximity Read ↗

Critical regions of the Vibrio fischeri luxR protein defined by mutational analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.