Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The quorum sensing transcriptional regulator TraR has separate binding sites for DNA and the anti-activator.

Biochemical and biophysical research communications - 10 Feb 2012

Zheng Zhida, Fuqua Clay, Chen Lingling

Abstract excerpt

Quorum sensing represents a mechanism by which bacteria control their genetic behaviors via diffusible signals that reflect their population density. TraR, a quorum sensing transcriptional activator in the Rhizobiaceae family, is regulated negatively by the anti-activator TraM via formation of a TraR-TraM heterocomplex. Prior structural analysis suggests that TraM and DNA bind to TraR in distinct sites. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Calorimetry
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Protein Conformation

Share to Quorum Sensing

Share to Rhizobium

Share to Thermodynamics

Source

Identifiers

PMID: 22274608
DOI: 10.1016/j.bbrc.2012.01.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The quorum sensing transcriptional regulator TraR has separate binding sites for DNA and the anti-activator.PMID 22274608Read ↗

Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR.Semantic proximity Read ↗

Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR.Semantic proximity Read ↗

Domains formed within the N-terminal region of the quorum-sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from agrobacterium.Semantic proximity Read ↗

Identification of amino acid residues of the pheromone-binding domain of the transcription factor TraR that are required for positive control.Semantic proximity Read ↗

Identification of amino acid residues of the Agrobacterium tumefaciens quorum-sensing regulator TraR that are critical for positive control of transcription.Semantic proximity Read ↗

The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.Semantic proximity Read ↗

A biochemical characterization of the DNA binding activity of the response regulator VicR from Streptococcus mutans.Semantic proximity Read ↗

N- and C-terminal regions of the quorum-sensing activator TraR cooperate in interactions with the alpha and sigma-70 components of RNA polymerase.Semantic proximity Read ↗

Dual control of quorum sensing by two TraM-type antiactivators in Agrobacterium tumefaciens octopine strain A6.Semantic proximity Read ↗

Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay.Semantic proximity Read ↗

Amino-terminal protein fusions to the TraR quorum-sensing transcription factor enhance protein stability and autoinducer-independent activity.Semantic proximity Read ↗

Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.