Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.

The Journal of biological chemistry - 17 Mar 2000

Luo Z Q, Qin Y, Farrand S K

Abstract excerpt

Conjugal transfer of Agrobacterium tumefaciens Ti plasmids is regulated by quorum sensing via the transcriptional activator TraR and the acyl-homoserine lactone Agrobacterium autoinducer (AAI). Unique to this system, the activity of TraR is negatively modulated by an antiactivator called TraM. An...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Agrobacterium tumefaciens
Share to Conjugation, Genetic
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homoserine

Share to Lactones

Share to Pheromones

Share to Repressor Proteins

Share to Transcriptional Activation

Source

Identifiers

PMID: 10713083
DOI: 10.1074/jbc.275.11.7713

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10713083-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The antiactivator TraM interferes with the autoinducer-dependent binding of TraR to DNA by interacting with the C-terminal region of the quorum-sensing activator.PMID 10713083Read ↗

Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraR.Semantic proximity Read ↗

Induction and loss of Ti plasmid conjugative competence in response to the acyl-homoserine lactone quorum-sensing signal.Semantic proximity Read ↗

Amino-terminal protein fusions to the TraR quorum-sensing transcription factor enhance protein stability and autoinducer-independent activity.Semantic proximity Read ↗

A new regulatory element modulates homoserine lactone-mediated autoinduction of Ti plasmid conjugal transfer.Semantic proximity Read ↗

Identification of amino acid residues of the Agrobacterium tumefaciens quorum-sensing regulator TraR that are critical for positive control of transcription.Semantic proximity Read ↗

Dual control of quorum sensing by two TraM-type antiactivators in Agrobacterium tumefaciens octopine strain A6.Semantic proximity Read ↗

Crystal structure of the quorum-sensing protein TraM and its interaction with the transcriptional regulator TraR.Semantic proximity Read ↗

Identification of amino acid residues of the pheromone-binding domain of the transcription factor TraR that are required for positive control.Semantic proximity Read ↗

Octopine-type Ti plasmids code for a mannopine-inducible dominant-negative allele of traR, the quorum-sensing activator that regulates Ti plasmid conjugal transfer.Semantic proximity Read ↗

Domains formed within the N-terminal region of the quorum-sensing activator TraR are required for transcriptional activation and direct interaction with RpoA from agrobacterium.Semantic proximity Read ↗

The quorum sensing transcriptional regulator TraR has separate binding sites for DNA and the anti-activator.Semantic proximity Read ↗

N- and C-terminal regions of the quorum-sensing activator TraR cooperate in interactions with the alpha and sigma-70 components of RNA polymerase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.