Article
HGF/SF-Met signaling in tumor progression.
Cell research - 1 Jan 2005
Gao Chong Feng, Vande Woude George F
Abstract excerpt
Tumor progression is a multi-step process that requires a sequential selection of specific malignant phenotypes. Met activation may induce different phenotypes depending on tumor stage: inducing proliferation and angiogenesis in primary tumors, stimulating motility to form micrometastases, and regaining the proliferation phenotype to form overt metastases. To study how HGF/SF-induced proliferative phenotypes...
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