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Article

Gene of the month: MET

22 Apr 2015

Abstract excerpt

The MET receptor tyrosine kinase and its ligand hepatocyte growth factor/scatter factor (HGF/SF) are potential therapeutic targets in many human malignancies, making this pathway an important focus of molecular and cancer research. MET mutations have been detected in various tumours. In addition, many tumour types demonstrate MET and HGF/SF overexpression and amplification. The MET signal transduction cascade is...

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Identifiers

PMID: 25987653
DOI: 10.1136/jclinpath-2015-203050

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