Article
Passive anti-PcrV treatment protects burned mice against Pseudomonas aeruginosa challenge.
Burns : journal of the International Society for Burn Injuries - 1 Mar 2005
Neely Alice N, Holder Ian A, Wiener-Kronish Jeanine P, Sawa Teiji
Abstract excerpt
The type III secretion system consists of secreted exoproducts and structural components, such as PcrV, and this system plays an important role in the virulence of Pseudomonas aeruginosa in burned hosts. The purpose of this study was to determine if passive anti-PcrV treatment would protect burned mice from fatal P. aeruginosa challenge, and to determine the type III exoproduct phenotype of the P. aeruginosa used...
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