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Multicomponent <i>Pseudomonas aeruginosa</i> vaccines eliciting Th17 cells and functional antibody responses confer enhanced protection against experimental acute pneumonia in mice

2022-05-05

Abstract excerpt

The Gram-negative pathogen Pseudomonas aeruginosa is a common cause of pneumonia in hospitalized patients. Its increasing antibiotic resistance and widespread occurrence present a pressing need for vaccines. We previously showed that a P. aeruginosa type III secretion system protein, PopB elicits a strong Th17 response in mice after intranasal (IN) immunization and confers antibody-independent protection against...

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Identifiers and source

Literature Corpus work
88a42ce3-37d1-5490-98bb-acfab190fff0
DOI
10.1101/2022.05.05.490820
Open publication

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Multicomponent <i>Pseudomonas aeruginosa</i> vaccines eliciting Th17 cells and functional antibody responses confer enhanced protection against experimental acute pneumonia in miceDOI 10.1101/2022.05.05.490820
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