Article
Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections.
The Journal of infectious diseases - 15 Jun 2001
Roy-Burman A, Savel R H, Racine S, Swanson B L, Revadigar N S, Fujimoto J, Sawa T, Frank D W, Wiener-Kronish J P
Abstract excerpt
The ability of Pseudomonas aeruginosa to secrete specific toxins using the type III-mediated pathway has been reported. To determine the association of this phenotype with human illness, immunoblot analysis was used to detect expression of type III secretory proteins in P. aeruginosa isolates from respiratory tract or blood cultures of 108 consecutive patients. Relative risk of mortality was 6-fold greater with...
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