A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates.

doi:10.1016/j.ijmm.2007.02.004

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Article

A genotypic and phenotypic comparison of type III secretion profiles of Pseudomonas aeruginosa cystic fibrosis and bacteremia isolates.

International journal of medical microbiology : IJMM - 1 Jul 2007

Wareham David W, Curtis Michael A

Abstract excerpt

The type III secretion system (TTSS) of Pseudomonas aeruginosa enables delivery of a number of toxins involved in the disruption of eukaryotic epithelial surfaces. Whilst the ability to secrete ExoS facilitates invasion and internalization, the secretion of ExoU mediates acute cytotoxicity. In order to determine any association with the ability to secrete these toxins with the nature and severity of human...

Topics

Bacteremia
Bacterial Proteins
Cystic Fibrosis
Genotype
Humans
Phenotype
Polymerase Chain Reaction
Pseudomonas aeruginosa
Random Amplified Polymorphic DNA Technique

Source

Open in PubMed

Identifiers

PMID: 17412636
DOI: 10.1016/j.ijmm.2007.02.004

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