Article
Neuroligins, synapse balance and neuropsychiatric disorders.
Pharmacological reports : PR - 1 Oct 2014
Maćkowiak Marzena, Mordalska Patrycja, Wędzony Krzysztof
Abstract excerpt
Neuroligins are postsynaptic adhesion molecules that are involved in the regulation of synapse organisation and function. Four neuroligin proteins have been identified (neuroligin 1, 2, 3, 4), which are differentially enriched in the postsynaptic specialisation of synapses. Neuroligin 1 is localised on excitatory (glutamatergic) synapses, whereas neuroligin 2 is located on inhibitory (GABAergic/glycinergic)...
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