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Article

In vitro mispairing specificity of O2-ethylthymidine.

Biochemistry - 5 May 1992

Grevatt P C, Solomon J J, Bhanot O S

Abstract excerpt

The O2-position of thymine is a major site of base alkylation by N-nitroso-alkylating agents, and its biological relevance remains obscure. The potential significance of this DNA damage was ascertained by studying in vitro DNA replication properties of O2-ethylthymidine (O2-Et-dT) site-specifically incorporated into a 36-nucleotide template. DNA replication was initiated eight nucleotides away from the O2-Et-dT...

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Identifiers

PMID: 1567865
DOI: 10.1021/bi00132a005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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