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Article

Imprinting, expression, and localisation of DLK1 in Wilms tumours.

Journal of clinical pathology - 1 Feb 2005

Fukuzawa R, Heathcott R W, Morison I M, Reeve A E

Abstract excerpt

BACKGROUND: Loss of imprinting (LOI) of the H19/IGF2 domain is a common feature of Wilms tumour. The GTL2/DLK1 domain is also imprinted and is structurally similar to H19/IGF2. The question arises as to whether DLK1 also undergoes LOI in Wilms tumour, or whether the LOI mechanism is restricted to the H19/IGF2 domain. AIM: To investigate the imprinting status of DLK1 in Wilms tumours with IGF2 LOI. The cellular...

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Source

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Identifiers

PMID: 15677533
DOI: 10.1136/jcp.2004.021717
PMCID: PMC1770562

Genes

DLK1
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Imprinting, expression, and localisation of DLK1 in Wilms tumours.PMID 15677533Read ↗

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Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors.Semantic proximity Read ↗

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