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Article

RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia.

Leukemia - 1 Mar 2005

Wiemels J L, Zhang Y, Chang J, Zheng S, Metayer C, Zhang L, Smith M T, Ma X, Selvin S, Buffler P A, Wiencke J K

Abstract excerpt

We explored the relationship of RAS gene mutations with epidemiologic and cytogenetic factors in a case series of children with leukemia. Diagnostic bone marrow samples from 191 incident leukemia cases from the Northern California Childhood Leukemia Study were typed for NRAS and KRAS codon 12 and 13 mutations. A total of 38 cases (20%) harbored RAS mutations. Among the 142 B-cell acute lymphoblastic leukemia...

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Source

Identifiers

PMID: 15674422
DOI: 10.1038/sj.leu.2403641

Genes

KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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