Article
Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11.
Biochemical and biophysical research communications - 4 Mar 2005
Babaya Naru, Ikegami Hiroshi, Fujisawa Tomomi, Nojima Koji, Itoi-Babaya Michiko, Inoue Kaori, Ohno Tamio, Shibata Masao, Ogihara Toshio
Abstract excerpt
To study the contribution of beta-cell vulnerability to susceptibility to diabetes, we studied beta-cell vulnerability to a single high dose of streptozotocin (STZ) in an animal model of type 2 diabetes, the NSY mouse, a sister strain of the STZ-sensitive NOD mouse, in comparison with the STZ-res...
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