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Article

Cellular transformation of NIH3T3 fibroblasts by CIZ/NMP4 fusions.

Journal of cellular biochemistry - 15 Apr 2005

Corveleyn Anniek, Janssen Hilde, Martini Alessandra, Somers Riet, Cools Jan, Marynen Peter

Abstract excerpt

Molecular cloning of the translocations t(12;22)(p13;q12) and t(12;17)(p13;q11) in acute leukaemia showed that either EWSR1 or its homologue TAF15 are fused to the transcription factor CIZ. EWSR1 and TAF15 belong to the TET family (TLS/FUS, EWSR1 and TAF15) of proteins. TET fusions have been identified in both solid tumours and acute myeloid leukaemia. The novel 12p translocations directly implicated TET fusions...

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Share to Artificial Gene Fusion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15669012
DOI: 10.1002/jcb.20369

Genes

TAF15
EWSR1
FUS
MMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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